What this means
Researchers will compare two enema programs to see which better prevents bowel accidents and is easier to manage. This is a study that is still recruiting, so no results are posted yet.
Plain-English summary written by an AI model from the registry listing.
- Status
- Recruiting
- Who can join
- Ages 5 and over
- Where
- 24 sites, including Alabama, Arizona, California
The science
- Registered title
- Bowel Continence Across the Lifespan in People With Spina Bifida
- Trial ID
- NCT07390318 ↗
- Phase
- Not applicable
- Study type
- observational
- Conditions
- Spina Bifida, Neurogenic Bowel, Bowel Incontinence
- What is tested
- Retrograde Enema, Antegrade Enema
- Sponsor
- David Chu
- Ages
- 5 Years to no maximum
- Dates
- First posted Feb 5, 2026 · updated Sep 24, 2026
Registry summary
The goal of this observational study is to learn how different enema programs affect bowel control in children and adults with spina bifida. An enema program involves putting liquid into the large intestine (colon) to help someone poop. The main questions it aims to answer are:
- How well do different enema programs prevent bowel accidents?
- How do these enema programs affect independence, bowel symptoms, and quality of life?
Researchers will compare two types of enema programs to see which works better and is easier for participants to manage.
Participants starting a new enema program will answer online survey questions at 3 different timepoints over the course of 1 year.
Sites (24)
- University of Alabama at Birmingham, Birmingham, Alabama, United States
- Children's of Alabama, Birmingham, Alabama, United States
- Phoenix Children's Hospital, Phoenix, Arizona, United States
- Children's Hospital of Los Angeles, Los Angeles, California, United States
- University of California San Francisco, San Francisco, California, United States
- Children's Hospital of Colorado, Denver, Colorado, United States
- Children's National Hospital, Washington D.C., District of Columbia, United States
- Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois, United States
- Northwestern University, Chicago, Illinois, United States
- Riley Children's Hospital, Indianapolis, Indiana, United States
- Boston Children's Hospital, Boston, Massachusetts, United States
- University of Michigan, Ann Arbor, Michigan, United States
- Duke University Medical Center, Durham, North Carolina, United States
- Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, United States
- Cleveland Clinic, Cleveland, Ohio, United States
And 9 more on the listing.
More aging trials in these states
Alabama · Arizona · California · Colorado · District of Columbia · Illinois · Indiana · Massachusetts · Michigan · North Carolina · Ohio · Pennsylvania · Tennessee · Texas · Utah · Washington