What this means
Researchers will watch adults for 12 weeks after a routine mouth-area skin procedure. This study is not yet finished, so it cannot tell us whether the procedure works.
Plain-English summary written by an AI model from the registry listing.
- Status
- Recruiting
- Who can join
- Ages 18 and over
- Where
- 1 site
The science
- Registered title
- Prospective, Non-interventional Study Assessing Perioral Rejuvenation Procedure
- Trial ID
- NCT07398768 ↗
- Phase
- Not applicable
- Study type
- observational
- Conditions
- Perioral Wrinkles, Crow's Feet, Lip Volume Enhancement, Lip Aging
- What is tested
- Saypha® Rich, Saypha® Filler Lidocaine
- Sponsor
- Yuvell
- Ages
- 18 Years to no maximum
- Dates
- First posted Feb 10, 2026 · updated Mar 13, 2026
Registry summary
The goal of this observational study is to learn how a perioral rejuvenation procedure affects perioral line severity and lip volume over time in adults undergoing routine aesthetic treatment in a single clinical center. The main questions it aims to answer are:
- What proportion of participants achieves a ≥1-point improvement from baseline on both the Lip Fullness Scale (LFS) and the Static Perioral Lines Assessment Scale (SPLAS) at Week 12?
- How do skin wrinkling/surface roughness, lip and perioral volume, and patient satisfaction change over 6 and 12 weeks?
Participants will:
- Receive a routine (non-study-mandated) holistic perioral rejuvenation procedure as decided by their treating clinician.
- Attend study visits at approximately baseline, Week 6, and Week 12.
- Undergo independent clinical assessments (assessor not involved in treatment delivery) of LFS and SPLAS.
- Have skin wrinkling and surface roughness documented by VISIA skin analysis (baseline, Week 6, Week 12).
- Have lip and perioral volume measured by VECTRA M3 volume analysis (baseline, Week 6, Week 12).
- Complete a standardized patient satisfaction questionnaire (Week 12).
Sites (1)
- YUVELL, Vienna, State of Vienna, Austria