What this means
This trial plans to test whether taking MitoQ daily for 3 months helps brain arteries work better. It has not started recruiting, and no results have been posted yet.
Plain-English summary written by an AI model from the registry listing.
- Status
- Opening soon
- Who can join
- Ages 60 and over
- Where
- 1 site, including Colorado
The science
- Registered title
- Oral Antioxidant Therapy Targeted to the Mitochondria for Improving Brain Artery Health in Postmenopausal Women
- Trial ID
- NCT07406243 ↗
- Phase
- Not applicable
- Study type
- interventional
- Conditions
- Aging, Postmenopause
- What is tested
- Mitoquinone (MitoQ), Placebo
- Sponsor
- Colorado State University
- Ages
- 60 Years to no maximum
- Dates
- First posted Feb 12, 2026 · updated Feb 12, 2026
Registry summary
The goal of this clinical trial is to learn if 3 months of taking the dietary supplement MitoQ [a mitochondria-targeted antioxidant that targets to reduce mitochondrial reactive oxygen species (mitoROS)] works to treat age- and menopause-related reductions in brain artery (cerebrovascular) function in postmenopausal women 60 years of age or older free of clinical disease. The main questions it aims to answer are:
Does MitoQ improve cerebrovascular function in postmenopausal women?
If so, does MitoQ improve cerebrovascular function by lowering mitoROS in these arteries?
Researchers will compare MitoQ to a placebo (a look-alike substance that contains no drug) to see if MitoQ can improve cerebrovascular function by lowering mitoROS in arteries involved in brain health and function.
Participants will:
Take MitoQ (20 mg/day) or a placebo every day for 3 months
Visit the research laboratory at baseline and then after 3 months for cerebrovascular testing; there is also a check-in visit at 6 weeks, which is the halfway point
Keep track of symptoms and events during their treatment period to report to the study team
Sites (1)
- Translational Physiology Laboratory within the Food Science Clinical Research Laboratory, Fort Collins, Colorado, United States