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Checking memory before hip surgery may predict confusion afterward

Recruiting · Tomas Bata Hospital, Czech Republic

What this means

This study plans to test a short memory screen before hip replacement surgery in older adults. It will track whether the screen predicts post-surgery confusion, called delirium. Results are not yet available, so it does not show whether the screen works.

Plain-English summary written by an AI model from the registry listing.

Status
Recruiting
Who can join
Ages 65 and over · 300-400 older adults aged 65 and up, planned across seven centers in the Czech Republic
Where
7 sites

Contacts and how to join ↗

The science

Registered title
Orthopedic Procedures and Postoperative Delirium in Older Adults in the Czech Republic
Phase
Not applicable
Study type
observational
Conditions
Frailty, Cognitive Impairment, Older Adults, Hip Arthroplasty, Postoperative Delirium
Sponsor
Tomas Bata Hospital, Czech Republic
Ages
65 Years to no maximum
Dates
First posted Feb 25, 2026 · updated Jul 9, 2026

Registry summary

This multicenter, prospective, non-interventional observational study (ORTOPODCZ) investigates the association between preoperative cognitive impairment and postoperative delirium (POD) in older adults undergoing elective total hip arthroplasty in the Czech Republic. Postoperative delirium is a frequent and serious neurocognitive complication in senior surgical patients and is associated with increased morbidity, mortality, prolonged hospitalization, and impaired functional and cognitive outcomes. Despite international recommendations, routine preoperative cognitive screening remains insufficiently implemented.

The study evaluates the predictive value of the ALBA test, a brief cognitive screening tool, performed during the pre-anesthetic assessment. Postoperative delirium will be assessed using the validated CAM-ICU instrument for up to 72 hours after surgery. Secondary objectives include assessing the relationship between POD and frailty, polypharmacy, comorbidities, type of anesthesia, intraoperative hemodynamics, blood loss, vasoactive support, and postoperative complications.

Approximately 300-400 participants aged ≥65 years will be enrolled across seven centers. No additional procedures, biological sampling, or deviations from standard clinical care are required. Data will be collected in REDCap and analyzed according to a predefined statistical analysis plan. The study aims to provide robust evidence supporting the integration of cognitive screening into routine preoperative evaluation and to describe feasibility and implementation requirements for the ALBA test in clinical practice.

Sites (7)

  • University Hospital Brno - Bohunice, Brno, Czechia
  • University Hospital Olomouc - Department of Anaesthesiology, Resuscitation and Intensive Care, Olomouc, Czechia
  • University Hospital Ostrava - Department of Anaesthesiology, Resuscitation and Intensive Care, Ostrava, Czechia
  • University Hospital Královské Vinohrady, Prague, Czechia
  • University Hospital Motol, Prague, Czechia
  • Vsetín Hospital, Vsetín, Czechia
  • Tomas Bata Regional Hospital, Zlín, Czechia
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