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Comparing walking, body makeup, and a blood protein in people with and without dementia

Opening soon · Universiti Sains Malaysia

What this means

This study is a plan to compare older adults with dementia and healthy older adults. It has not started yet and has no results. It cannot yet tell us whether these measures can detect dementia early.

Plain-English summary written by an AI model from the registry listing.

Status
Opening soon
Who can join
Ages 50 and over
Where
1 site

Contacts and how to join ↗

The science

Registered title
Cognitive-Frailty Gait Biomechanics for Early Dementia Detection
Phase
Not applicable
Study type
observational
Conditions
Mild Cognitive Impairment (MCI)
Sponsor
Universiti Sains Malaysia
Ages
50 Years to no maximum
Dates
First posted Mar 4, 2026 · updated Mar 4, 2026

Registry summary

The purpose of this study is to better understand how physical characteristics, walking patterns, and a blood-based brain health marker differ between older adults with dementia and healthy older adults.

Dementia is often associated with changes in physical health and movement, but these changes are not fully understood. This study asks whether people with dementia show differences in body composition, walking ability, and levels of brain-derived neurotrophic factor (BDNF), a protein involved in brain function, compared with individuals without dementia.

To answer this question, participants will complete a single assessment session that includes basic physical measurements, an assessment of walking while moving at a comfortable pace, and a small blood sample collection. The information collected will be used to compare the two groups and explore possible relationships between physical function, walking patterns, and BDNF levels.

Sites (1)

  • School of Health Sciences, Kota Bharu, Kelantan, Malaysia
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