What this means
This study is recruiting people to test whether a 12-week supplement and supervised exercise plan helps strength, gut health, immune function, and thinking. No results have been posted yet, so we do not know if it works.
Plain-English summary written by an AI model from the registry listing.
- Status
- Recruiting
- Who can join
- Ages 50–80
- Where
- 1 site
The science
- Registered title
- Exploratory Study on a Multi-nutrient Supplement and Exercise Program for Improving Health Markers Associated to Longevity in Pre-frail Adults
- Trial ID
- NCT07454616 ↗
- Phase
- Not applicable
- Study type
- interventional
- Conditions
- Pre-Frailty, Aging
- What is tested
- Supervised exercise program, a balanced micronutrient blend
- Sponsor
- National University of Singapore
- Ages
- 50 Years to 80 Years
- Dates
- First posted Mar 6, 2026 · updated Mar 6, 2026
Registry summary
Frailty is associated with biological changes in the gut microbiome and immune system, along with marked declines in physical and cognitive function, leading to an overall reduction in quality of life. Prefrailty represents an early stage where interventions may prevent or reverse these declines. This study aims to evaluate whether a 12-week combined Synbiotic enriched oral nutritional supplement and supervised exercise program can improve muscle strength and mass, gut microbiome composition, immune function, and cognitive performance in prefrail adults aged 50-80 years.
Sites (1)
- MD11 Clinical Research Centre, #03-01, 10 Medical Drive, Singapore, Singapore