What this means
This is a planned trial that will compare a structured care plan with usual palliative care. It will test whether the plan helps symptoms, mood, and care satisfaction, but no results have been reported yet.
Plain-English summary written by an AI model from the registry listing.
- Status
- Recruiting
- Who can join
- Ages 18 and over
- Where
- 1 site
The science
- Registered title
- MultidISciplinary Care paThway tailoRed on frAilty in Cancer Patients Referred to Outpatient paLliative Care
- Trial ID
- NCT07469761 ↗
- Phase
- Not applicable
- Study type
- interventional
- Conditions
- Palliative Care, Palliative Care, Health Services, Patient Reported Outcome (PRO), Patient Reported Outcome Measurements, Frailty, Cancer, Outpatient
- What is tested
- Structured Palliative Care, Classical Palliative Care
- Sponsor
- Augusto Caraceni
- Ages
- 18 Years to no maximum
- Dates
- First posted Mar 13, 2026 · updated Mar 13, 2026
Registry summary
The goal of this clinical trial is to learn whether a structured, Patient-Reported Outcome Measures (PROMs)-tailored palliative care pathway improves clinical outcomes and care experience in adults with advanced cancer referred to outpatient palliative care.
Patients with advanced cancer often experience multiple symptoms and complex needs. Standard outpatient palliative care is usually guided by clinical judgment on patient-reported questionnaires. In this study, researchers aim to test whether a more structured approach, based on predefined cut-offs from PROMs, can improve symptom control, satisfaction with care, and use of healthcare resources. The main questions the study aims to answer are:
Does a structured, PROM-driven palliative care pathway reduce symptom burden and psychological distress compared with usual care? And through this, to improve patients' and caregivers' satisfaction with care or reduce emergency room visits, hospital admissions, healthcare costs, and aggressive treatments near the end of life?
Researchers will compare two groups:
Control group: Participants will receive standard outpatient palliative care. PROMs are collected as usual, but without predefined cut-offs or structured intervention checklists.
Experimental group: Participants will receive a structured palliative care pathway tailored to symptoms/needs identified at baseline using PROM cut-offs. Specific multidisciplinary interventions are activated according to identified needs.
Sites (1)
- IRCCS Istituto Nazionale dei Tumori, Via Venezian n1, Milan, Lombardy, Italy