What this means
This study will measure how often blood pressure drops too much after standing or eating in hospitalized adults aged 65 and older. It has not reported results yet, so it does not tell us how common these drops are.
Plain-English summary written by an AI model from the registry listing.
- Status
- Opening soon
- Who can join
- Ages 65 and over
- Where
- 1 site
The science
- Registered title
- Orthostatic And Postprandial Hypotension In Hospitalized Older Adults (HOPE65)
- Trial ID
- NCT07485998 ↗
- Phase
- Not applicable
- Study type
- observational
- Conditions
- Orthostatic Hypotension, Postprandial Hypotension
- Sponsor
- University Medical Centre Ljubljana
- Ages
- 65 Years to no maximum
- Dates
- First posted Mar 20, 2026 · updated Mar 20, 2026
Registry summary
The goal of this observational study is to determine how often orthostatic hypotension and postprandial hypotension occur in adults aged 65 years and older who are hospitalized in internal medicine departments.
Orthostatic hypotension is defined as an excessive drop in blood pressure after standing up from a lying or sitting position. Postprandial hypotension is an excessive drop in blood pressure that occurs after eating a meal. These conditions can increase the risk of falls, fainting, loss of independence, and other health problems in older adults.
The main questions this study aims to answer are:
- How common orthostatic hypotension and postprandial hypotension are in hospitalized adults aged 65 years and older.
- Whether these conditions are associated with medication use, chronic diseases, and geriatric syndromes (such as frailty, cognitive impairment, and functional decline).
Participants will:
- have blood pressure measured while lying down and standing
- have blood pressure measured after a meal
- undergo a comprehensive geriatric assessment, including evaluation of functional status, cognitive function, frailty, mobility, and nutritional status
- provide information about medications and medical history
- be followed for up to 12 months to record outcomes such as falls, syncope, hospitalization, and death
Sites (1)
- University Medical Centre Ljubljana, Ljubljana, Slovenia