What this means
This is a trial registration, so the study is planned or running but has not reported results. It does not yet tell us whether fucoidan affects aging or DNA changes in people.
Plain-English summary written by an AI model from the registry listing.
- Status
- Recruiting
- Who can join
- Ages 50–80
- Where
- 2 sites
The science
- Registered title
- Project SIRT6 Activator
- Trial ID
- NCT07500649 ↗
- Phase
- Not applicable
- Study type
- interventional
- Conditions
- Aging
- What is tested
- Fucoidan, Placebo
- Sponsor
- National University of Singapore
- Ages
- 50 Years to 80 Years
- Dates
- First posted Mar 30, 2026 · updated Mar 30, 2026
Registry summary
The global ageing population is increasingly affected by age-related diseases, which are challenging healthcare systems. Current treatments often extend lifespan without improving healthspan. The geroscience hypothesis suggests that targeting the ageing process could prevent or delay multiple diseases, enhancing healthspan. Fucoidan, a sulfated polysaccharide from brown macroalgae, is a safe dietary supplement with Sirtuin-6 (SIRT6) activating properties, which are linked to longevity. Clinical studies have shown that it reduces inflammatory markers associated with biological aging and frailty and influences DNA methylation in vitro and in vivo; however, its effects on human DNA methylation remain unknown.
Sites (2)
- Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore, Singapore
- NUS Academy for Healthy Longevity, Level 6, MD 11, 10 Medical Dr, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore