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Testing exercise to build strength and fitness in frail older adults

Recruiting · The Hong Kong Polytechnic University

What this means

This trial plans to test whether three months of aerobic and resistance exercise helps frail older adults. It has not reported results, so we do not yet know if it works.

Plain-English summary written by an AI model from the registry listing.

Status
Recruiting
Who can join
Ages 60–90 · Older adults with physical frailty, enrollment still open
Where
1 site

Contacts and how to join ↗

The science

Registered title
Enhancing Physical Reserve to Promote Resilience in Physically Frail Older Adults
Phase
Not applicable
Study type
interventional
Conditions
Frailty at Older Adults
What is tested
Aerobic and resistance training, Usual Care
Sponsor
The Hong Kong Polytechnic University
Ages
60 Years to 90 Years
Dates
First posted Apr 7, 2026 · updated Sep 25, 2026

Registry summary

The goal of this clinical trial is to assess the efficacy of combined aerobic and resistance training in enhancing physical reserve in older adults with physical frailty. Investigator contend that enhanced physical reserve will enable preservation of cognitive and physical function. The main questions aims to answer are: (1) Compared with usual care (i.e., CON), will 3-month aerobic and resistance training (ATRT) improve physical reserve in older adults with physical frailty? (2) Compared with CON, will ATRT lead to changes in the neural network organization? (3) Will improved physical reserve lead to better maintenance of cognitive and physical functioning in spite of presence of white matter hyperintensities (WMH)?

Sites (1)

  • The Hong Kong Polytechnic University, Department of Rehabilitation Sciences, Hong Kong, Hong Kong, Hong Kong

Related treatments

Exercise

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