What this means
This is a study plan, and it has not reported results yet. It will test whether a prep program helps older adults with breast cancer, and it will look at body markers linked to frailty.
Plain-English summary written by an AI model from the registry listing.
- Status
- Recruiting
- Who can join
- Ages 65 and over
- Where
- 1 site
The science
- Registered title
- Multicomponent Prehabilitation in Older Adults With Breast Cancer
- Trial ID
- NCT07531836 ↗
- Phase
- Not applicable
- Study type
- interventional
- Conditions
- Breast Cancer, Frailty, Sarcopenia, Aging, Functional Decline
- What is tested
- Home-based Multicomponent Prehabilitation (Vivifrail), Supervised Multicomponent Prehabilitation, Comprehensive Geriatric Assessment and Optimization
- Sponsor
- Fundacion Miguel Servet
- Ages
- 65 Years to no maximum
- Dates
- First posted Apr 15, 2026 · updated Sep 29, 2026
Registry summary
Older adults with breast cancer frequently present with frailty, decreased functional reserve, and increased risk of postoperative complications. Prehabilitation programs have emerged as a promising strategy to improve physical function and clinical outcomes; however, evidence in geriatric oncology remains limited, particularly regarding the role of biological markers in predicting response to such interventions.
This study aims to evaluate the effectiveness of a multicomponent prehabilitation program in older adults with breast cancer, focusing on functional status, clinical outcomes, and quality of life. In addition, the study seeks to characterize biological markers associated with frailty and treatment response, with the goal of identifying potential predictors of benefit from prehabilitation.
Participants will undergo a structured prehabilitation intervention including physical exercise, nutritional optimization, and comprehensive geriatric assessment. Clinical, functional, and biomarker data will be collected longitudinally.
The results of this study may contribute to improving personalized care strategies in geriatric oncology and to identifying patients who are most likely to benefit from prehabilitation programs.
Sites (1)
- Hospital Universitario de Navarra, Pamplona, Navarre, Spain