What this means
Researchers plan to measure how many of 300 adults with obesity also have sarcopenia, a loss of muscle mass and strength. They also plan to look at factors linked to it, such as age and physical activity.
Plain-English summary written by an AI model from the registry listing.
- Status
- Recruiting
- Who can join
- Ages 21–100 · 300 adults with obesity at a specialized Obesity Center
- Where
- 1 site
The science
- Registered title
- Investigating the Prevalence and Risk Factors for Sarcopenia Amongst Adults Seeking Treatment for Obesity
- Trial ID
- NCT07541677 ↗
- Phase
- Not applicable
- Study type
- observational
- Conditions
- Obesity
- Sponsor
- Singapore General Hospital
- Ages
- 21 Years to 100 Years
- Dates
- First posted Apr 21, 2026 · updated Apr 21, 2026
Registry summary
Sarcopenia, a condition where individuals lose muscle mass and strength, is associated with poorer health and function. While aging is a well-known cause of sarcopenia, obesity is increasingly recognised as a significant factor. When sarcopenia and obesity occur together, it can result in more severe health problems. This is especially concerning because weight loss, the treatment for obesity, can further reduce muscle mass and potentially worsen the situation. Despite this, it is unknown how common sarcopenia is among people with obesity, as only a few studies have looked into this using the most accurate diagnostic criteria, showing a prevalence of 4-13%.
In this study, the investigators will examine the prevalence of sarcopenia in 300 adults with obesity at a specialized Obesity Center. The investigators expect to find a higher prevalence among Asian participants due to differences in body composition compared to other ethnic groups.
The investigators will also explore various factors that might be linked to sarcopenia in these individuals, such as age, gender, race, body mass index, smoking and alcohol use, medical conditions, medications, physical activity, aerobic capacity, and dietary protein intake. Some of these factors could help in identifying those at risk of sarcopenia and could be targeted for future treatments.
Currently, screening for sarcopenia is not a standard part of routine obesity care as it requires specialized equipment and trained staff. By determining how common sarcopenia is in people with obesity, this study will help healthcare providers better understand the problem and allocate resources effectively. Identifying factors associated with sarcopenia will also help streamline diagnosis and monitoring for those at risk.
Sites (1)
- Singapore General Hospital, Singapore, Singapore
