What this means
A trial will compare video-based exercise at home with a caregiver-led home exercise program. It has not started yet, so we do not know if it will help.
Plain-English summary written by an AI model from the registry listing.
- Status
- Opening soon
- Who can join
- Ages 65 and over
- Where
- Not listed
The science
- Registered title
- High-technology TeleRehabilitation for the Treatment of the FRAgile Patient
- Trial ID
- NCT07561021 ↗
- Phase
- Not applicable
- Study type
- interventional
- Conditions
- Heart Failure, Prefrail Elderly, Frail Elderly Syndrome
- What is tested
- Telerehabilitation, Caregiver-Supervised Home Exercise Program
- Sponsor
- University of Salerno
- Ages
- 65 Years to no maximum
- Dates
- First posted May 1, 2026 · updated May 7, 2026
Registry summary
The aim of this randomized controlled clinical trial is to evaluate the efficacy of an 8-week sensorimotor and cognitive telerehabilitation program in frail and pre-frail older adults with stable chronic heart failure. The study will compare a synchronous telerehabilitation intervention with a caregiver-supervised home exercise program. The primary question is whether telerehabilitation improves functional capacity, measured by change in peak oxygen uptake (VO₂peak) on cardiopulmonary exercise testing, more than the control intervention. A key secondary question is whether telerehabilitation improves frailty status, measured by the Italian Frailty Index (IFI), compared with the control group. Secondary outcomes include quality of life, physical performance, cognitive function, treatment adherence, caregiver burden and stress, and selected biomarkers related to heart failure and frailty. Participants will undergo baseline and follow-up clinical, functional, cognitive, and laboratory assessments and will be followed for up to 24 weeks.