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Planned study of blood vessel aging in older adults

Opening soon · National Institute of Cardiology, Laranjeiras, Brazil

What this means

This is a plan for a study that has not started recruiting people yet. It aims to test simple, non-invasive scans that might spot early signs of vessel aging.

Plain-English summary written by an AI model from the registry listing.

Status
Opening soon
Who can join
Ages 60–100
Where
1 site

Contacts and how to join ↗

The science

Registered title
Vascular Aging and Microcirculation: Physiological Aspects of Vascular Aging in the Elderly Population (VAMP-Aging)
Phase
Not applicable
Study type
observational
Conditions
Aging Problems
What is tested
Laser Speckle Contrast Imaging, Handgrip Dynamometry (Muscle Strength), Sit-to-Stand Test (5-Times Sit-to-Stand - 5STS), Single-Leg Balance Test, Assessment of Global Cognitive Function
Sponsor
National Institute of Cardiology, Laranjeiras, Brazil
Ages
60 Years to 100 Years
Dates
First posted May 4, 2026 · updated May 4, 2026

Registry summary

Rising life expectancy worldwide challenges public health due to increased cardiovascular disease linked to vascular aging, where microvascular dysfunction serves as an early indicator of system-wide inflammation, or "inflammaging". The proposed study aims to validate non-invasive, high-resolution techniques, such as Laser Speckle Contrast Imaging, to identify early endothelial senescence biomarkers and map their correlation with metabolic, inflammatory, and anthropometric profiles to advance personalized, preventive translational medicine.

Sites (1)

  • Eduardo Tibiriçá, Rio de Janeiro, Brazil
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