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A new study will look at a brain chemical system in aging and Parkinson's

Recruiting · Hospices Civils de Lyon

What this means

This study is still recruiting people, so no results are available yet. It aims to measure a brain signal system in healthy older adults and people with Parkinson's disease.

Plain-English summary written by an AI model from the registry listing.

Status
Recruiting
Who can join
Ages 20–80
Where
1 site

Contacts and how to join ↗

The science

Registered title
In Vivo Noradrenergic System and Aging
Phase
Not applicable
Study type
interventional
Conditions
Healthy Aging and Parkinson's Disease
What is tested
PET/MRI scanning session, Neuropsychological examination, Olfactory screening
Sponsor
Hospices Civils de Lyon
Ages
20 Years to 80 Years
Dates
First posted May 6, 2026 · updated Jul 9, 2026

Registry summary

The main goal of this research proposal is to provide, for the first time in humans, a wider understanding of the role of the noradrenergic system both in health and illness (here Parkinson's disease) through the use of a newly developed radiotracer visualizing alpha2C-ARs ([11C]ORM-13070) combined with a cutting-edge technology, the hybrid PET/MRI scanner. The secondary aim will be to determine whether the expected age- and PD-related changes in the noradrenergic system are paralleled by changes in neuropsychological performances (i.e. cognitive, motor and/or olfactory abilities).

Sites (1)

  • Hôpital Neurologique Pierre Wertheimer - Service de Neurologie, Bron, France
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