What this means
Researchers plan a 12-week trial of a drink with inulin fiber, with or without B-vitamins, in older adults. The trial has not reported results, so it cannot yet show whether the drink helps gut health or mood.
Plain-English summary written by an AI model from the registry listing.
- Status
- Recruiting
- Who can join
- Ages 50 and over
- Where
- 1 site
The science
- Registered title
- Effect of a Food Intervention With a Prebiotic Alone or Combined With B-vitamins on Gut Microbiota Diversity, Inflammation and Mental Health Outcomes in Older Adults (GutFood)
- Trial ID
- NCT07592975 ↗
- Phase
- Not applicable
- Study type
- interventional
- Conditions
- Biomarkers of B-vitamin Status and Gut Microbiome Composition
- What is tested
- Inulin and B-vitamins, Inulin, Placebo
- Sponsor
- University of Ulster
- Ages
- 50 Years to no maximum
- Dates
- First posted May 18, 2026 · updated May 18, 2026
Registry summary
Ageing is associated with changes in gut microbiota composition, increased inflammation, and a greater risk of poor mental health outcomes. Nutritional inadequacies, including low dietary fibre intake and suboptimal B-vitamin status, are common in older adults and may contribute to these age-related health issues. Research suggests that increasing dietary fibre intake, particularly through prebiotics such as inulin, may help to improve gut health. In addition, B-vitamins have been linked to both gut and mental health, although their combined effects with prebiotics are not well understood.
With the assistance of a food company, the investigators have developed a functional drink enriched with chicory inulin, alone or in combination with B-vitamins. Therefore, the investigators plan to conduct a 12-week randomised, double-blind, placebo-controlled trial to test the effect of this functional drink on gut health outcomes, nutritional status, inflammation, and mental health in adults aged 50 years and older.
Sites (1)
- Human Intervention Studies Unit, Coleraine, County Londonderry, United Kingdom