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Brain activity during walking tasks in people after stroke

Recruiting · Karolinska Institutet

What this means

Researchers will measure brain activity and walking while people after stroke do tasks like walking and thinking at once. This is a plan for a study that is still recruiting, so no results exist yet.

Plain-English summary written by an AI model from the registry listing.

Status
Recruiting
Who can join
Ages 18 and over
Where
1 site

Contacts and how to join ↗

The science

Registered title
Walking and Thinking - Brain Activity During Complex Walking in Stroke
Phase
Not applicable
Study type
observational
Conditions
Stroke, Aging, Neuro-Degenerative Disease, Gait Impairment in Stroke Patients
What is tested
No Interventions
Sponsor
Karolinska Institutet
Ages
18 Years to no maximum
Dates
First posted Jun 3, 2026 · updated Jun 3, 2026

Registry summary

Everyday life requires individuals to function in complex environments and perform tasks that involve the integration of motor and cognitive abilities. However, stroke often leads to impairments in motor-cognitive interaction, which can negatively affect mobility, balance, attention, and the ability to live independently. Although motor-cognitive performance has been identified as an important rehabilitation target after stroke, limited knowledge exists regarding the underlying brain function associated with these difficulties and how rehabilitation and exercise interventions can best address them.

Improving treatment for motor-cognitive difficulties after stroke, such as dual-task walking and navigation, remains a major challenge. An important step is developing assessment methods that accurately capture these impairments in ecologically valid settings that reflect real-world mobility demands. The investigators therefore aim to explore brain function during complex walking after stroke by investigating motor-cognitive performance and its neural correlates during three walking conditions: dual-task walking, navigation, and a combination of both. Non-invasive measures of brain activity using functional near-infrared spectroscopy (fNIRS) together with advanced real-time gait analysis will be used to better understand how stroke affects motor-cognitive functioning during complex walking tasks.

Sites (1)

  • uMOVE core facility, Karolinska Institutet and Karolinska University hospital, Solna, Stockholm County, Sweden

Related treatments

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