What this means
This study plans to check whether a blood test score before surgery is linked to blood pressure drops after anesthesia starts. It has not started reporting results, so it cannot yet show whether the score predicts anything.
Plain-English summary written by an AI model from the registry listing.
- Status
- Recruiting
- Who can join
- Ages 18 and over · 160 frail adults planned for non-cardiac surgery
- Where
- 1 site
The science
- Registered title
- EASIX Score and Post-Induction Hypotension in Frail Patients Undergoing Non-Cardiac Surgery
- Trial ID
- NCT07642765 ↗
- Phase
- Not applicable
- Study type
- observational
- Conditions
- Hypotension on Induction, Frailty, Anesthesia, General
- What is tested
- EASIX Score Assessment
- Sponsor
- Konya City Hospital
- Ages
- 18 Years to no maximum
- Dates
- First posted Jun 11, 2026 · updated Aug 4, 2026
Registry summary
Post-induction hypotension (PIH) is a common and clinically significant hemodynamic complication following general anesthesia induction. Frail patients are particularly vulnerable due to impaired vascular reactivity and endothelial dysfunction. The Endothelial Activation and Stress Index (EASIX), calculated from routine laboratory parameters (LDH, creatinine, and platelet count), may serve as a preoperative biomarker to identify patients at risk for PIH.
This prospective observational cohort study aims to evaluate the association between preoperative EASIX score and the occurrence of post-induction hypotension in frail patients undergoing elective non-cardiac surgery under general anesthesia. A total of 160 patients with a Clinical Frailty Scale (CFS) score of 4 or above will be enrolled. Mean arterial pressure will be measured every 2 minutes for the first 15 minutes after induction. PIH is defined as MAP below 65 mmHg and/or a decrease of 20% or more from baseline.
Sites (1)
- Konya City Hospital, Konya, Turkey (Türkiye)