What this means
Researchers plan to test smell, thinking, blood markers, and scans in older adults over time. The study has not started yet, so it cannot tell us what causes smell loss or how to treat it.
Plain-English summary written by an AI model from the registry listing.
- Status
- Opening soon
- Who can join
- Ages 50 and over
- Where
- 1 site, including South Carolina
The science
- Registered title
- Olfactory Dysfunction in Aging Adults
- Trial ID
- NCT07660887 ↗
- Phase
- Not applicable
- Study type
- observational
- Conditions
- Olfactory Dysfunction
- What is tested
- Clinical and Biomarker Assessments
- Sponsor
- Medical University of South Carolina
- Ages
- 50 Years to no maximum
- Dates
- First posted Jun 22, 2026 · updated Jun 22, 2026
Registry summary
This prospective longitudinal cohort study will enroll adults aged 50 years and older to characterize olfactory dysfunction in aging. Participants will undergo comprehensive olfactory testing, cognitive assessment, biomarker collection, and imaging to identify clinically relevant phenotypes based on anatomic site of dysfunction. The study will also evaluate the impact of olfactory dysfunction on quality of life and identify baseline factors associated with changes in olfactory function over time.
Sites (1)
- MUSC, Charleston, South Carolina, United States