What this means
This trial plans to compare a light exercise with a cuff against heavy weights in young and older adults. It has not started, so no results are available yet.
Plain-English summary written by an AI model from the registry listing.
- Status
- Opening soon
- Who can join
- Ages 18 and over
- Where
- 1 site
The science
- Registered title
- Acute Autonomic Responses During and After BFR Training
- Trial ID
- NCT07722403 ↗
- Phase
- Not applicable
- Study type
- interventional
- Conditions
- Blood Flow Restriction Exercise, Aging
- What is tested
- High-Intensity Resistance Training (HIRT), Low-Intensity Resistance Training with Blood Flow Restriction (LIRT-BFR)
- Sponsor
- Egas Moniz - Cooperativa de Ensino Superior, CRL
- Ages
- 18 Years to no maximum
- Dates
- First posted Jul 23, 2026 · updated Jul 23, 2026
Registry summary
The goal of this clinical trial is to compare how the body's nervous system responds to two different types of leg exercise in young and older adults. One type is low-intensity exercise with blood flow restriction (BFR) , where a cuff partially reduces blood flow to the legs during exercise. The other type is traditional high-intensity resistance training (HIRT), which uses heavier weights.
The main questions it aims to answer are:
Does low-intensity exercise with BFR cause less stress on the nervous system during exercise compared to high-intensity training? Does low-intensity exercise with BFR lead to faster recovery of the nervous system after exercise compared to high-intensity training? Do these responses differ between young adults and older adults? Researchers will compare low-intensity exercise with BFR to high-intensity training to see which approach is gentler on the nervous system during and after exercise.
Participants will:
Attend three visits to the research lab Complete a strength test on leg exercise machines Perform two separate exercise sessions: one with low-intensity exercise and BFR, and one with high-intensity training Have their heart rate, blood pressure, and heart rate variability monitored continuously during and after each exercise session
Sites (1)
- Egas Moniz School of Health and Science, Almada, Monte Da Caparica, Portugal