What this means
This is a planned trial that has not started recruiting or reported results. It will test whether the program reduces frailty and improves quality of life and confidence in managing care.
Plain-English summary written by an AI model from the registry listing.
- Status
- Opening soon
- Who can join
- Ages 18 and over
- Where
- Not listed
The science
- Registered title
- Developing and Testing the Effectiveness of Smart Healthcare Assisted Individualized Symptom Management Education and Home-based Exercise on Frailty, Treatment-related Adverse Events and Quality of Life in Advanced Gastric Cancer Patients Receiving Immunotherapy
- Trial ID
- NCT07732543 ↗
- Phase
- Not applicable
- Study type
- interventional
- Conditions
- Gastric Cancer (GC), Immunotherapy
- What is tested
- AI-ISME&HE
- Sponsor
- Taipei Veterans General Hospital, Taiwan
- Ages
- 18 Years to no maximum
- Dates
- First posted Jul 29, 2026 · updated Jul 29, 2026
Registry summary
The goal of this randomized controlled intervention is to develop and evaluate the effectiveness of the nurse-led with AI chatbot Individualized Symptom Management Education and Home-based Exercise (AI-ISME\&HE) based on The Theory of Symptom Self-Management (TSSM) on frailty, self-efficacy in cancer care, trAE, and quality of life in advanced gastric cancer patients receiving immunotherapy. The main questions it aims to answer are:
- Can AI-ISME\&HE reduces frailty in advanced gastric cancer patients receiving immunotherapy?
- Can AI-ISME\&HE increases quality of life in advanced gastric cancer patients receiving immunotherapy?
- Can AI-ISME\&HE increases self-efficacy in advanced gastric cancer patients receiving immunotherapy?
- Can AI-ISME\&HE reduces all-caused death in advanced gastric cancer patients receiving immunotherapy within two years? Researchers will compare usual routine care to see if AI-ISME\&HE can reduce frailty, all-caused death and increase quality of life and self-efficacy.
Participants will not be blinded, but the outcome evaluator will be blinded. The participants will be asked to complete three tasks for 12 weeks:
- Self-reporting treatment-related adverse events
- Interacting with AI-ISME\&HE for seeking information related to self-management educational materials, including symptom management with the most reported trAEs and prevention from frailty
- ViviFrail-based exercise