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Will a supplement called AKG help older adults' brains? A trial is planned

Opening soon · PHASE 2 · University of Oklahoma

What this means

Researchers plan to test whether AKG, a supplement, helps brain responses and thinking in older adults. This trial has not started and has no results yet, so it cannot show whether AKG works.

Plain-English summary written by an AI model from the registry listing.

Status
Opening soon
Who can join
Ages 55 and over
Where
Not listed

Contacts and how to join ↗

The science

Registered title
AKG and Brain Health in Aging
Phase
PHASE 2
Study type
interventional
Conditions
Brain Aging, Cerebrovascular Function
What is tested
Calcium AKG, Oral placebo capsules
Sponsor
University of Oklahoma
Ages
55 Years to no maximum
Dates
First posted Oct 6, 2026 · updated Oct 6, 2026

Registry summary

This proposal will test the hypothesis that AKG supplementation will improve NGVC responses and cognitive performance in older adults. We will also test the hypothesis that these effects are mediated by a decrease in age-related oxidative stress within NGVU cells.

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