Saturday, October 17, 2026 · Edition updated 6:00 AM ETSAT, OCT 17 · 6 AM ET editionNext edition in Next --:--:--

What's new, in plain English

Gathered every morning from PubMed, bioRxiv, medRxiv, ClinicalTrials.gov and the FDA. Each item links to its original source.

New trial · ClinicalTrials.gov · Oct 134Metformin

Small pilot tests drug and digital tracking for healthy aging in older adults

A small study gave 31 adults in Israel one of two drug mixes for about eight weeks and tracked them with phone-based checks. The study did not report results yet, so it cannot tell us whether either approach helps.

Tested in 31 adults aged 50 to 80

Original title: ELITE: Deep Profiling and Algorithmic Polytherapy to Map Individual Response in Healthy Aging

New trial · ClinicalTrials.gov · Oct 15

Study checks if a blood-based aging test predicts IVF success

Researchers planned to compare a blood measure of biological age in women who did and did not have a live birth after IVF. This registration has no results yet, so it does not tell us whether the test predicts success.

Original title: Epigenetic Clock to Predict Ovarian Aging and Live Birth in ART

Results posted · ClinicalTrials.gov · Mar 254Exercise

Study compares muscle tiredness in younger and older adults and tests strength training

Researchers plan to compare younger and older adults to learn why leg muscles tire faster with age. They also plan to test an 8 week strength program, with and without blood flow restriction, in older adults.

Original title: Fatigability of Lower Limb Muscle in Older Adults: Protective Effects of Strength Training Exercise in Old Men and Women

Opening soon · ClinicalTrials.gov · Oct 132Fisetin

A planned trial will test fisetin, a natural compound, in older adults

This trial plans to test whether fisetin, a natural compound, can improve blood vessel function in older adults. It also plans to check safety, and whether people keep taking it, but it has not started and has no results yet.

Original title: Fisetin for Improving Vascular Function in Older Adults: A Phase II Clinical Trial

Now recruiting · ClinicalTrials.gov · Oct 144Exercise

Can light weight training with blood flow limits help colon cancer survivors with muscle loss?

This is a trial plan that has not reported results yet. It will test whether the training improves strength, daily movement, and tiredness.

Original title: Low Load Blood Flow Restriction Resistance Training in Colorectal Cancer Related Sarcopenia

Now recruiting · ClinicalTrials.gov · Oct 14

A filler device for facial wrinkles is being tested in 43 adults

This study plans to check how well a gel device works for facial wrinkles and whether it is safe. The study has not reported any results yet, so it cannot show whether the device works.

Tested in 43 adults aged 18 to 65 at one clinic in Italy

Original title: Evaluation of the Performance and Safety of the MD60000 Device in the Treatment of Skin Imperfections Due to Aging.

Opening soon · ClinicalTrials.gov · Oct 13

Testing whether a switch to doravirine/islatravir changes aging markers in people with HIV

This is a planned study that has not started enrolling people yet, so no results exist. It will not tell us anything about aging effects until it runs and reports.

Original title: Effects of Switch to Doravirine/Islatravir vs. Continued Antiretroviral Therapy on Biomarkers of Aging Among Virologically Suppressed People With HIV

New trial · ClinicalTrials.gov · Oct 154Exercise

Testing balance and walking after a 4-week AI-guided exercise program

This study plans to check balance, walking, and brain activity before and after 4 weeks of exercise. It has not reported results, so it cannot yet show whether the program helps.

Tested in 50 adults aged 52 to 65

Original title: Short-term Changes in Postural Sway, Gait, and fNIRS-derived Cortical Metrics After a 4-week AI-assisted Exercise Program: a Single-arm Pre-post Study

Opening soon · ClinicalTrials.gov · Oct 134Exercise

Testing a traditional Chinese exercise against resistance training for muscle loss

This is a plan for a study, and it has not started recruiting people yet. It does not tell us yet whether the exercise works, because no results have been posted.

Tested in 240 adults aged 50 or older with sarcopenia, at six hospitals in Beijing

Original title: Yijinjing Exercise for Musculoskeletal Health in Adults With Sarcopenia